Fibrosis can also affect internal organs and can lead to impairment or failure of the affected organs.
“This may be followed by puffy or swollen hands before the skin becomes thickened and hard. The signs and symptoms of systemic scleroderma usually begin with episodes of Raynaud’s phenomenon, which can occur weeks to years before fibrosis. “The fibrosis is caused by the body’s production of too much collagen, which normally strengthens and supports connective tissues.
According to the National Institutes for Health, the disorder is “characterized by the buildup of scar tissue in the skin and other organs.” Systemic scleroderma is an autoimmune disorder that affects the skin and internal organs. She had to move to Los Angeles to live with my parents because she needed so much help. “She got treatment, but it was just treating her symptoms with drugs like prednisone and cortisone. She was 44 when she was diagnosed with systemic scleroderma,” he told NIH Medline Plus Magazine in 2019. “My sister, Gay Saget, was a school teacher near Philadelphia. Saget was a longtime supporter of the Scleroderma Research Foundation, an organization that raises funds for research into the autoimmune disorder that claimed his sister Gay’s life in 1994.
By Debbie Lord, Cox Media Group National Content Desk Januat 3:22 pm ESTĪs people learned about the death of comedian Bob Saget, many close to him suggested that a donation to research into a medical condition his sister suffered with and died from would be a fitting tribute to the star of the 1980s and 90s sitcom “Full House.”